Impact of Preterm Premature Rupture of Membranes on Composite Adverse Perinatal Outcomes and Associated Predictors Among Pregnant Women in Tigray, Northern Ethiopia: A Prospective Cohort Study
This prospective cohort study in Tigray, Northern Ethiopia, demonstrates that preterm premature rupture of membranes (PPROM) significantly increases the risk of composite adverse perinatal outcomes, with independent predictors including prior pregnancy infections, lack of iron-folate supplementation, pelvic pain, and a latency period of 1–3 days.